RFX6 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52780-20UL
60 ul
£183.00
E-AB-52780-60UL
120 ul
£272.00
E-AB-52780-120UL
200 ul
£420.00
E-AB-52780-200UL
About this Product
- SKU:
- E-AB-52780
- Additional Names:
- 6,DNA binding protein RFX6 ,RFX6,RFX6 regulatory factor X,Regulatory factor X domain containing protein 1
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.84 mg/ml
- Extra Details:
- The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human RFX6
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-rfx6_polyclonal_antibody-e_ab_52780
