PSMD12 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52752-20UL
60 ul
£183.00
E-AB-52752-60UL
120 ul
£272.00
E-AB-52752-120UL
200 ul
£420.00
E-AB-52752-200UL
About this Product
- SKU:
- E-AB-52752
- Additional Names:
- 26S proteasome non-ATPase regulatory subunit 12,26S proteasome regulatory subunit RPN5,26S proteasome regulatory subunit p55,MGC75406,PSD12,PSMD12,Proteasome 26S non ATPase subunit 12 isoform 2,R,macropain) 26S subunit,non ATPase12,p55,proteasome (prosome
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.9 mg/ml
- Extra Details:
- The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human PSMD12
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-psmd12_polyclonal_antibody-e_ab_52752
