POLH Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52741-20UL
60 ul
£183.00
E-AB-52741-60UL
120 ul
£272.00
E-AB-52741-120UL
200 ul
£420.00
E-AB-52741-200UL
About this Product
- SKU:
- E-AB-52741
- Additional Names:
- DNA polymerase eta,FLJ16395,FLJ21978,POLH,Polh,RAD30,RAD30 homolog A,RAD30A,XP V,XPV,Xeroderma pigmentosum variant type protein,polymerase DNA directed eta
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.78 mg/ml
- Extra Details:
- This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA, when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human POLH
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-polh_polyclonal_antibody-e_ab_52741
