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Antibodies

ADRM1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52740-20UL
60 ul
£183.00
E-AB-52740-60UL
120 ul
£272.00
E-AB-52740-120UL
200 ul
£420.00
E-AB-52740-200UL
About this Product
SKU:
E-AB-52740
Additional Names:
000 surface antigen;110 kDa cell membrane glycoprotein;ADRM 1;ADRM1;ARM 1;ARM-1;ARM1;Adhesion-regulating molecule 1;Adrm1;Gp110;M(r) 110;Proteasomal ubiquitin receptor ADRM1;adhesion regulating molecule 1;hRpn13;proteasome regulatory particle non ATPase 1
Application:
Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
0.54 mg/ml
Extra Details:
The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.
Host:
Rabbit
Immunogen:
Fusion protein of human ADRM1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody