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Antibodies

PSPC1 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52739-20UL
60 ul
£183.00
E-AB-52739-60UL
120 ul
£272.00
E-AB-52739-120UL
200 ul
£420.00
E-AB-52739-200UL
About this Product
SKU:
E-AB-52739
Additional Names:
PSP1,PSPC1,Paraspeckle component 1,Paraspeckle protein 1,Pspc1
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.48 mg/ml
Extra Details:
This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles.These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins.Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism.The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase.Alternative splicing of this gene results in multiple transcript variants.A related pseudogene, which is also located on chromosome 13, has been identified.
Host:
Rabbit
Immunogen:
Fusion protein of human PSPC1
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody