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Antibodies

HBG1/HBG2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52690-20UL
60 ul
£183.00
E-AB-52690-60UL
120 ul
£272.00
E-AB-52690-120UL
200 ul
£420.00
E-AB-52690-200UL
About this Product
SKU:
E-AB-52690
Additional Names:
A gamma globin,G gamma globin,Gamma 1 globin,Gamma 2 globin,Gamma A hemoglobin,Gamma globin,HBG 1,HBG 2,HBG1,HBG2,HBGA,HBGR,Hb F Agamma,Hb F Ggamma,Hemoglobin gamma,Hemoglobin gamma 1 chain ,Hemoglobin gamma 2 chain ,Hemoglobin gamma A,hbfagamma,hbfggamma
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.84 mg/ml
Extra Details:
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Host:
Rabbit
Immunogen:
Fusion protein of human HBG1/HBG2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody