TUBGCP4 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52657-20UL
60 ul
£183.00
E-AB-52657-60UL
120 ul
£272.00
E-AB-52657-120UL
200 ul
£420.00
E-AB-52657-200UL
About this Product
- SKU:
- E-AB-52657
- Additional Names:
- 76P,FLJ14797,GCP 4,GCP4,Gamma tubulin complex component 4,Gamma tubulin ring complex protein,Gamma tubulin ring complex protein (76p gene),Gamma-ring complex protein 76 kDa,Grip76,Hgrip76,TUBGCP 4,TUBGCP4,Tubulin gamma complex associated protei,h76p,hGCP4
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.66 mg/ml
- Extra Details:
- This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human TUBGCP4
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-tubgcp4_polyclonal_antibody-e_ab_52657
