IGHA1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52649-20UL
60 ul
£183.00
E-AB-52649-60UL
120 ul
£272.00
E-AB-52649-120UL
200 ul
£420.00
E-AB-52649-200UL
About this Product
- SKU:
- E-AB-52649
- Additional Names:
- FLJ14473;FLJ35065;FLJ35500;FLJ36402;FLJ39698;FLJ40001;FLJ41548;FLJ41552;FLJ41789;FLJ43248;FLJ43594;FLJ44293;FLJ46028;FLJ46621;FLJ46724;FLJ46811;FLJ46824;FLJ90170;IGHA1;Ig alpha 1 chain C region;IgA1;MGC102857;immunoglobulin heavy constant alpha 1
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 0.9 mg/ml
- Extra Details:
- Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human IGHA1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Secondary Antibodies
- Manufacturer's Data Sheet:p-igha1_polyclonal_antibody-e_ab_52649
