IL6ST Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52510-20UL
60 ul
£183.00
E-AB-52510-60UL
120 ul
£272.00
E-AB-52510-120UL
200 ul
£420.00
E-AB-52510-200UL
About this Product
- SKU:
- E-AB-52510
- Additional Names:
- CDW,IL6ST,CD130,CDW130,GP130,IL-6RB,Interleukin 6 signal transducer,IR6RB,CD130 antigen,GP130 RAPS,IL 6R beta,IL-6 receptor subunit beta,IL6 ST,IL-6R subunit beta,IL6RB,IL-6R-beta,Interleukin 6 receptor subunit beta,Interleukin receptor beta chain,Interleukin-6 receptor subunit beta,Interleukin-6 signal transducer,Membrane glycoprotein 130,Membrane glycoprotein gp130,Oncostatin M receptor,Oncostatin M receptor alpha subunit,Oncostatin-M receptor subunit alpha
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human IL6ST
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-il6st_polyclonal_antibody-e_ab_52510
