C7 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52507-20UL
60 ul
£183.00
E-AB-52507-60UL
120 ul
£272.00
E-AB-52507-120UL
200 ul
£420.00
E-AB-52507-200UL
About this Product
- SKU:
- E-AB-52507
- Additional Names:
- C7,CO7,Complement component C7,complement component 7
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. C7 (Complement C7) is a Protein Coding gene. Diseases associated with C7 include C7 Deficiency and Immunodeficiency Due To A Late Component Of Complement Deficiency. Among its related pathways are Complement Pathway and Innate Immune System. An important paralog of this gene is C6.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human C7
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-c7_polyclonal_antibody-e_ab_52507
