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Antibodies

C4BPB Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52505-20UL
60 ul
£183.00
E-AB-52505-60UL
120 ul
£272.00
E-AB-52505-120UL
200 ul
£420.00
E-AB-52505-200UL
About this Product
SKU:
E-AB-52505
Additional Names:
C4BP,C4BPB,C4b binding protein beta chain,C4b-binding protein beta chain,Complement component 4 binding protein beta,Complement component 4 binding protein beta chain,Complement component 4-binding protein beta,OTTHUMP00000034288,OTTHUMP00000034289
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.7 mg/ml
Extra Details:
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids.A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway.C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster.Alternative splicing gives rise to multiple transcript variants.
Host:
Rabbit
Immunogen:
Fusion protein of human C4BPB
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody