C1orf101 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52492-20UL
60 ul
£183.00
E-AB-52492-60UL
120 ul
£272.00
E-AB-52492-120UL
200 ul
£420.00
E-AB-52492-200UL
About this Product
- SKU:
- E-AB-52492
- Additional Names:
- C1orf101,CA101,Chromosome 1 Open Reading Frame 101,RP11-523K4.1,Uncharacterized protein C1orf101
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.6 mg/ml
- Extra Details:
- Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf101 gene product has been provisionally designated C1orf101 pending further characterization.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human C1orf101
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-c1orf101_polyclonal_antibody-e_ab_52492
