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Antibodies

BLNK Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52474-20UL
60 ul
£183.00
E-AB-52474-60UL
120 ul
£272.00
E-AB-52474-120UL
200 ul
£420.00
E-AB-52474-200UL
About this Product
SKU:
E-AB-52474
Additional Names:
AGM4,B cell adapter containing SH2 domain protein,B cell adapter containing Src homology 2 domain protein,B cell adaptor containing SH2 domain,B cell linker,B cell linker protein,B cell-specific adaptor protein,B-cell activation,B-cell adapter containing
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.1 mg/ml
Extra Details:
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development.This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions.The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation.Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked.Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.
Host:
Rabbit
Immunogen:
Fusion protein of human BLNK
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody