PHF21A Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52472-20UL
60 ul
£183.00
E-AB-52472-60UL
120 ul
£272.00
E-AB-52472-120UL
200 ul
£420.00
E-AB-52472-200UL
About this Product
- SKU:
- E-AB-52472
- Additional Names:
- BHC80a,BM-006,BRAF35-HDAC complex protein BHC80,BRAF35/HDAC2 complex (80 kDa),KIAA1696,PF21A,PHD finger protein 21A,PHF21A
- Application:
- Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.7 mg/ml
- Extra Details:
- Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. PHF21A (PHD finger protein 21A), also known as BRAF35-HDAC complex protein BHC80, is a 680 amino acid nuclear protein that contains one PHD-type zinc finger and one A.T hook DNA-binding domain, suggesting involvement in transcriptional regulation events. PHF21A is a component of the BHC complex, which is responsible for repressing transcription of neuron-specific genes in non-neuronal cells. The BHC complex acts as a chromatin modifier that deacetylates and demethylates specific sites on histones. PHF21A may act as a scaffold within the BHC complex. Predominantly expressed in brain, three isoforms of PHF21A exist as a result of alternative splicing events.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human PHF21A
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-phf21a_polyclonal_antibody-e_ab_52472
