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Antibodies

UBA7 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52436-20UL
60 ul
£183.00
E-AB-52436-60UL
120 ul
£272.00
E-AB-52436-120UL
200 ul
£420.00
E-AB-52436-200UL
About this Product
SKU:
E-AB-52436
Additional Names:
D8,MGC12713,UBA1,UBA1B,UBA7,UBE 2,UBE1L,UBE2,Ube 1L,Ubiquitin Activating Enzyme E1 Like,Ubiquitin activa,Ubiquitin activating enzyme 2,Ubiquitin activating enzyme E1 homolog,ubiquitin activating enzyme E1,ubiquitin activating enzyme E1 homolog B
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.6 mg/ml
Extra Details:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.
Host:
Rabbit
Immunogen:
Fusion protein of human UBA7
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody