VRK1 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52422-20UL
60 ul
£183.00
E-AB-52422-60UL
120 ul
£272.00
E-AB-52422-120UL
200 ul
£420.00
E-AB-52422-200UL
About this Product
- SKU:
- E-AB-52422
- Additional Names:
- MGC117401,MGC138280,MGC142070,PCH1,PCH1A,Serine/threonine protein kinase VRK1,Serine/threonine-protein kinase VRK1,VRK1,Vaccinia related kinase 1 ,Vaccinia virus B1R related kinase 1,Vaccinia-related kinase 1
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases.This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas.Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination.This gene, therefore, may regulate cell proliferation.This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human VRK1
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-vrk1_polyclonal_antibody-e_ab_52422
