GCLC Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52359-20UL
60 ul
£183.00
E-AB-52359-60UL
120 ul
£272.00
E-AB-52359-120UL
200 ul
£420.00
E-AB-52359-200UL
About this Product
- SKU:
- E-AB-52359
- Additional Names:
- EC 6.3.2.2,GCL,GCS,GCS heavy chain,GLCL,GLCLC,GSH1,Gamma ECS,Gamma glutamylcysteine synthetase,Gamma-ECS,Gamma-glutamylcysteine synthetase,Gclc,Glutamate cysteine ligase catalytic subunit,Glutamate--cysteine ligase catalytic subunit
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human GCLC
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-gclc_polyclonal_antibody-e_ab_52359
