LRRC19 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52280-20UL
60 ul
£183.00
E-AB-52280-60UL
120 ul
£272.00
E-AB-52280-120UL
200 ul
£420.00
E-AB-52280-200UL
About this Product
- SKU:
- E-AB-52280
- Additional Names:
- FLJ21302,LRC19,LRRC 19,LRRC19,Leucine rich repeat containing 19,Leucine-rich repeat-containing protein 19,leucine rich repeat containing protein 19
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1.1 mg/ml
- Extra Details:
- LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human LRRC19
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-lrrc19_polyclonal_antibody-e_ab_52280
