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Antibodies

PRAME Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52200-20UL
60 ul
£183.00
E-AB-52200-60UL
120 ul
£272.00
E-AB-52200-120UL
200 ul
£420.00
E-AB-52200-200UL
About this Product
SKU:
E-AB-52200
Additional Names:
4930534P07Rik,CT130,Cancer/testis antigen 130,MAPE,Melanoma antigen preferentially expressed in tumors,OIP 4,OIP-4,OIP4 ,OPA interacting protein 4,OPA-interacting protein 4,Opa interacting protein OIP4,PRAME,Preferentially expressed antigen in melan
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.1 mg/ml
Extra Details:
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Fusion protein of human PRAME
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody