PRKAR2A Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52196-20UL
60 ul
£183.00
E-AB-52196-60UL
120 ul
£272.00
E-AB-52196-120UL
200 ul
£420.00
E-AB-52196-200UL
About this Product
- SKU:
- E-AB-52196
- Additional Names:
- cAMP dependent protein kinase regulatory subunit RII alpha,cAMP dependent protein kinase regulatory subunit alpha 2,cAMP dependent protein kinase type II alpha regulatory chain,cAMP dependent protein kinase type II alpha regulatory subunit,cAMP-dependent
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 0.8 mg/ml
- Extra Details:
- cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
- Host:
- Rabbit
- Immunogen:
- Fusion protein of human PRKAR2A
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-prkar2a_polyclonal_antibody-e_ab_52196
