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Antibodies

MAPK8 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52157-20UL
60 ul
£183.00
E-AB-52157-60UL
120 ul
£272.00
E-AB-52157-120UL
200 ul
£420.00
E-AB-52157-200UL
About this Product
SKU:
E-AB-52157
Additional Names:
AI849689,C-JUN kinase 1,EC 2.7.11.24,JNK,JNK 1,JNK-46,JNK1A2,JNK21B1/2,MAP kinase 8,MAPK 8,MK08,Mitogen activated protein kinase 8,Mitogen-activated protein kinase 8,Prkm8,Protein kinase ,c Jun N terminal kinase 1,c-Jun N-terminal kinase 1,mapk8,p54 gamma
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.9 mg/ml
Extra Details:
MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1,PRKM8,SAPK1,SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73,mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.
Host:
Rabbit
Immunogen:
Fusion protein of human MAPK8
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody