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Antibodies

ROCK2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52117-20UL
60 ul
£183.00
E-AB-52117-60UL
120 ul
£272.00
E-AB-52117-120UL
200 ul
£420.00
E-AB-52117-200UL
About this Product
SKU:
E-AB-52117
Additional Names:
KIAA0619,Rho associated,Rho associated coiled coil containing protein kinase 2,Rho associated protein kinase 2,Rho kinase 2,Rho-associa,Rho-associated,coiled coil containing protein kinase II,coiled-coil-containing protein kinase 2,p164 ROCK 2,p164 ROCK-2
Application:
Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.78 mg/ml
Extra Details:
The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4.
Host:
Rabbit
Immunogen:
Fusion protein of human ROCK2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody