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Antibodies

KCNN2 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52083-20UL
60 ul
£183.00
E-AB-52083-60UL
120 ul
£272.00
E-AB-52083-120UL
200 ul
£420.00
E-AB-52083-200UL
About this Product
SKU:
E-AB-52083
Additional Names:
Apamin sensitive small conductance Ca2+ activated potassium,Apamin sensitive small conductance Ca2+ activated potassium channel,KCa2.2,Kcnn2,Potassium intermediate/small conductance calcium a,Potassium intermediate/small conductance calcium activated,hSK2
Application:
Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
0.78 mg/ml
Extra Details:
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. KCNN2 (Potassium Calcium-Activated Channel Subfamily N Member 2) is a Protein Coding gene. Among its related pathways are Serotonergic synapse and Bile secretion. GO annotations related to this gene include protein homodimerization activity and ion channel activity. An important paralog of this gene is KCNN3.
Host:
Rabbit
Immunogen:
Synthetic peptide of human KCNN2
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody