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Antibodies

JAM3 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-52059-20UL
60 ul
£183.00
E-AB-52059-60UL
120 ul
£272.00
E-AB-52059-120UL
200 ul
£420.00
E-AB-52059-200UL
About this Product
SKU:
E-AB-52059
Additional Names:
FLJ14529,JAM 2 ,JAM 3,JAM C,JAM-2,JAM-3,JAM-C,JAM2 ,JAM3,JAMC,Jam3,Junctional adhesion molecule 3,Junctional adhesion molecule 3 precursor,Junctional adhesion molecule C
Application:
Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1.32 mg/ml
Extra Details:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.
Host:
Rabbit
Immunogen:
Synthetic peptide of human JAM3
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody