IL4R Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-52020-20UL
60 ul
£183.00
E-AB-52020-60UL
120 ul
£272.00
E-AB-52020-120UL
200 ul
£420.00
E-AB-52020-200UL
About this Product
- SKU:
- E-AB-52020
- Additional Names:
- 582J;IL4R;CD124;IL-4RA;IL4RA;IL-4 receptor subunit alpha;IL-4-binding protein;IL4-BP;IL-4R subunit alpha;IL-4R-alpha;Interleukin-4 receptor subunit alpha;582J2.1;IL-4RαIL 4R alpha;IL4R nirs variant 1;IL4RA;Interleukin 4 receptor;Interleukin 4 receptor alpha chain;sIL4Ralpha/prot;Soluble IL-4 receptor subunit alpha;Soluble IL-4R-alpha;Soluble interleukin-4 receptor subunit alpha
- Application:
- Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Concentration:
- 1.26 mg/ml
- Extra Details:
- This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of human IL4R
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-il4r_polyclonal_antibody-e_ab_52020
