Phospho-DDR1 (Tyr513) Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-51058-20UL
60 ul
£183.00
E-AB-51058-60UL
120 ul
£272.00
E-AB-51058-120UL
200 ul
£420.00
E-AB-51058-200UL
About this Product
- SKU:
- E-AB-51058
- Additional Names:
- CAK,CD 167,CD167,CD167 antigen-like family member A,CD167a,Cell adhesion kinase,DDR,DDR 1,DDR1,Discoidin domain receptor,Discoidin domain receptor tyrosine kinase 1,Discoidin receptor tyrosine kinase,Discoidin receptor tyrosine kinase isoform a,EDDR
- Application:
- Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. DDR1 (Discoidin Domain Receptor Tyrosine Kinase 1) is a Protein Coding gene. Diseases associated with DDR1 include Pulmonary Fibrosis, Idiopathic and Breast Cancer. Among its related pathways are GPCR Pathway and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is DDR2.
- Host:
- Rabbit
- Immunogen:
- Synthesized phospho derived from human DDR1 (Phospho-Tyr513)
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-phospho_ddr1_(tyr513)_polyclonal_antibody-e_ab_51058
