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Antibodies

PAI1 Polyclonal Antibody

Product Sizes
25 ul
£134.00
E-AB-40651-25UL
100 ul
£291.00
E-AB-40651-100UL
About this Product
SKU:
E-AB-40651
Additional Names:
Endothelial plasminogen activator inhibitor, PAI-1, PLANH1, SERPINE1, Serpin E1,Plasminogen activator inhibitor 1
Application:
Western Blot
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.
Host:
Rabbit
Immunogen:
Recombinant Rat PAI1 protein expressed by Mammalian
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody