GTPase Kras Polyclonal Antibody
Product Sizes
25 ul
£134.00
E-AB-40639-25UL
100 ul
£291.00
E-AB-40639-100UL
About this Product
- SKU:
- E-AB-40639
- Additional Names:
- GTPase Kras,K-Ras 2,KRAS,KRAS2,Ki-Ras,RASK2,c-K-ras,c-Ki-ras
- Application:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- KRAS,also called p21,is a member of the Ras superfamily of proteins. It is located on human chromosome 12,and contains four coding exons and a 5' non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family,the KRAS protein is a GTPase,and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies,including lung adenocarcinoma,mucinous adenoma,ductal carcinoma of the pancreas and colorectal carcinoma.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human KRAS protein expressed by E.coli.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-gtpase_kras_polyclonal_antibody-e_ab_40639
