DnaseIPolyclonal Antibody
Product Sizes
25 ul
£134.00
E-AB-40592-25UL
100 ul
£291.00
E-AB-40592-100UL
About this Product
- SKU:
- E-AB-40592
- Additional Names:
- DNASE1, DNL1, DRNI,Deoxyribonuclease-1
- Application:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Deoxyribonuclease I (DNase I) is an endonuclease which is secreted to cleave DNA in the extracellular space down to an average of tetranucleotides with 5' monophosphate and 3' hydroxyl DNA ends . Both single-stranded DNA and double-stranded DNA are degraded by Dnase I. This nuclease appears to account for the major nucleolytic activity on DNA in serum and is responsible for the degradation of the majority of circulating DNA derived from apoptotic and necrotic cell death and from neutrophil extracellular traps. In addition to its role in the serum, it has been proposed as one of the deoxyribonucleases responsible for DNA fragmentation in the process of apoptosis.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DnaseI protein expressed by E.coli.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-dnaseⅰpolyclonal_antibody-e_ab_40592
