CXCL12/SDF1 Polyclonal Antibody
Product Sizes
25 ul
£134.00
E-AB-40578-25UL
100 ul
£291.00
E-AB-40578-100UL
About this Product
- SKU:
- E-AB-40578
- Additional Names:
- SDF-1,Cxcl12
- Application:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The stromal cell derived factor 1 (SDF1/CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1/CXCL12 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1/CXCL12 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1/CXCL12 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1/CXCL12 isoforms (SDF1/CXCL12A Alpha and SDF1/CXCL12B Beta) that have different properties and biological activities. Additional isoforms of SDF1/CXCL12 have been reported.
- Host:
- Rabbit
- Immunogen:
- Recombinant Rat CXCL12 protein expressed by E.coli.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:sdf1_polyclonal_antibody-e_ab_40578
