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Antibodies

S100A4 Polyclonal Antibody

Product Sizes
25 ul
£134.00
E-AB-40458-25UL
100 ul
£291.00
E-AB-40458-100UL
About this Product
SKU:
E-AB-40458
Additional Names:
42A, CAPL, Calvasculin, FSP1, Fibroblast specific protein 1, Leukemia multidrug resistance associated protein, MTS1, Malignant transformation suppression 1, Metastasin, OTTHUMP00000015467, OTTHUMP00000015468, P9KA, PEL98, calcium Placental protein,18A2
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
Host:
Rabbit
Immunogen:
Recombinant Human Protein S100-A4 protein
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody