BBC3 Polyclonal Antibody
Product Sizes
25 ul
£134.00
E-AB-40332-25UL
100 ul
£291.00
E-AB-40332-100UL
About this Product
- SKU:
- E-AB-40332
- Additional Names:
- BBC 3;BBC3;BCL 2 binding component 3;BCL2 binding component 3;Bbc3;Bcl-2-binding component 3;JFY 1;JFY-1;JFY1;PUMA alpha;PUMA/JFY1;p53 Upregulated Modulator of Apoptosis;p53 up regulated modulator of apoptosis;p53 up-regulated modulator of apoptosis
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Bcl-2-binding component 3 protein
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-bbc3_polyclonal_antibody-e_ab_40332
