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Antibodies

Lamin B1 Polyclonal Antibody

Product Sizes
25 ul
£97.00
E-AB-40257-25UL
100 ul
£171.00
E-AB-40257-100UL
About this Product
SKU:
E-AB-40257
Additional Names:
ADLD,LMN,LMN2,LMNB,LMNB1,Lamin-B1,Lmnb1,MGC111419,OTTHUMP00000159218,lamin B1
Application:
Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Host:
Rabbit
Immunogen:
Recombinant Rat Lamin-B1 protein expressed by E.coli
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody