MCM7 Polyclonal Antibody
Product Sizes
25 ul
£134.00
E-AB-40231-25UL
100 ul
£291.00
E-AB-40231-100UL
About this Product
- SKU:
- E-AB-40231
- Additional Names:
- S. cerevisiae, formerly, homolog of,CDABP0042,CDC 47,CDC47,CDC47 homolog,Cdc47,DNA replication licensing factor MCM7,Homolog of S. cerevisiae Cdc47,MCM 2,MCM 7,MCM2,MCM7 minichromosome maintenance deficient 7,MCM7_HUMAN,Mcm7,Minichromosome Maintaine
- Application:
- Immunohistochemistry
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA replication licensing factor MCM7 protien
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-mcm7_polyclonal_antibody-e_ab_40231
