MCM3 Polyclonal Antibody
Product Sizes
25 ul
£134.00
E-AB-40230-25UL
100 ul
£291.00
E-AB-40230-100UL
About this Product
- SKU:
- E-AB-40230
- Additional Names:
- Cervical cancer proto oncogene 5,DNA polymerase alpha holoenzyme associated P1,HCC 5,HCC5,Human cervical cancer proto oncogene 5,MCM 3,MGC1157,Minichromosome maintenance complex component 3,P1 MCM3,P1 h,P1.h,Replication licensing fa,hRlf beta subunit,p102
- Application:
- Immunohistochemistry, Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human DNA replication licensing factor MCM3 protein
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-mcm3_polyclonal_antibody-e_ab_40230
