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Antibodies

FAS Polyclonal Antibody

Product Sizes
25 ul
£134.00
E-AB-40063-25UL
100 ul
£291.00
E-AB-40063-100UL
About this Product
SKU:
E-AB-40063
Additional Names:
ALPS 1A,ALPS1A,APO 1,APO 1 cell surface antigen,APO1,APO1 cell surface antigen,APT 1,APT1,Apo 1 antigen,Apo-1 antigen,Apo1 antigen,Apoptosis antigen 1,Apoptosis mediating surface antigen FAS,Apoptosis-mediating surface antigen FAS,CD 95,CD 95 antigen,CD95
Application:
Immunohistochemistry, Western Blot
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediates apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.
Host:
Rabbit
Immunogen:
Recombinant human Tumor necrosis factor receptor superfamily member 6 protein
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody