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Antibodies

NFK KappaB-p105/p50 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-32226-20UL
60 ul
£183.00
E-AB-32226-60UL
120 ul
£272.00
E-AB-32226-120UL
200 ul
£420.00
E-AB-32226-200UL
About this Product
SKU:
E-AB-32226
Additional Names:
DKFZp686C01211,DNA binding factor KBF1,DNA binding factor KBF1 EBP1,DNA-binding factor KBF1,EBP 1,EBP-1,EBP1,KBF1,MGC54151,NF kB1,NF kappa B,NF kappaB,NF kappabeta,NFKB 1,NFKB p105,NFKB p50,NFKB1,NFkappaB,Nfkb1,Nuclear factor kappa B DNA binding subu,nf b
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human NFK KappaB-p105/p50 around the non-phosphorylation site of Ser337.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody