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Antibodies

HDAC5 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-31647-20UL
60 ul
£183.00
E-AB-31647-60UL
120 ul
£272.00
E-AB-31647-120UL
200 ul
£420.00
E-AB-31647-200UL
About this Product
SKU:
E-AB-31647
Additional Names:
Antigen NY CO 9,Antigen NY-CO-9,HD5,HDAC 5,HDAC5,Histone deacetylase 5,NY CO 9
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human HDAC5 around the non-phosphorylation site of Ser498.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody