ERK 1/2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-31372-20UL
60 ul
£183.00
E-AB-31372-60UL
120 ul
£272.00
E-AB-31372-120UL
200 ul
£420.00
E-AB-31372-200UL
About this Product
- SKU:
- E-AB-31372
- Additional Names:
- ERK-1,ERK1,ERT2,Extracellular signal-regulated kinase 1,Insulin-stimulated MAP2 kinase,MAP kinase 3,MAP kinase isoform p44,MAPK 3,MAPK3,Microtubule-associated protein 2 kinase,Mitogen-activated protein kinase 3,PRKM3,p,p44-MAPK
- Application:
- Immunofluorescence, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human ERK 1/2 around the non-phosphorylation site of Thr202.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:2_polyclonal_antibody-e_ab_31372
