c-Fos Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-30899-20UL
60 ul
£183.00
E-AB-30899-60UL
120 ul
£272.00
E-AB-30899-120UL
200 ul
£420.00
E-AB-30899-200UL
About this Product
- SKU:
- E-AB-30899
- Additional Names:
- AP 1,Activator protein 1,C FOS,Cellular oncogene c fos,Cellular oncogene fos,FBJ Oste,FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS),FBJ murine osteosarcoma viral oncogene homolog,FBJ murine osteosarcoma viral v fos oncogene homolog
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from the N-terminal region of human c-Fos
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-c_fos_polyclonal_antibody-e_ab_30899
