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Antibodies

CASP9 Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-30760-20UL
60 ul
£183.00
E-AB-30760-60UL
120 ul
£272.00
E-AB-30760-120UL
200 ul
£420.00
E-AB-30760-200UL
About this Product
SKU:
E-AB-30760
Additional Names:
APAF-3;APAF3;Apoptosis related cysteine peptidase;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3;CASP-9;CASP9;Caspase 9 Dominant Negative;Caspase 9 apoptosis related cysteine peptidase;Caspase 9c;Caspase-9;Caspase-9 subunit p10;ICE
Application:
IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125.
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody