BCL-x Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-30640-20UL
60 ul
£183.00
E-AB-30640-60UL
120 ul
£272.00
E-AB-30640-120UL
200 ul
£420.00
E-AB-30640-200UL
About this Product
- SKU:
- E-AB-30640
- Additional Names:
- Apoptosis regulator Bcl X,Apoptosis regulator Bcl-X,Apoptosis regulator BclX,B cell lymphoma 2 like,B2CL1,BCL XL/S,BCL2L,BCLX,Bcl 2 like 1 protein,Bcl X,Bcl xL,Bcl xS,Bcl-2-like protein 1,Bcl2 Like 1,Bcl2 related gene,Bcl2-L-1,Bcl2l1,BclXL,BclXs,DKFZp781P
- Application:
- IHC-Paraffin, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Bcl x is a member of the Bcl 2 family of proteins, which function as regulators of apoptosis. It may provide neuroprotection against ischemic brian injury. Bcl x has two isoforms, Bcl xl (long) a 241 amino acid protein and Bcl xs (short) a 178 amino acid protein lacking a 63 amino acid domain that is well conserved among members of the Bcl2 family. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human Bcl-x around the non-phosphorylation site of Thr47.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:p-bcl_x_polyclonal_antibody-e_ab_30640
