AMPK alpha1/2 Polyclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-30491-20UL
60 ul
£183.00
E-AB-30491-60UL
120 ul
£272.00
E-AB-30491-120UL
200 ul
£420.00
E-AB-30491-200UL
About this Product
- SKU:
- E-AB-30491
- Additional Names:
- 5'-AMP-activated protein kinase catalytic subunit alpha-1,ACACA kinase,AMPK,AMPK subunit alpha-1,AMPK1,Acetyl-CoA carboxylase kinase,HMGCR kinase,Hydroxymethylglutaryl-CoA reductase kinase,PRKAA1,PRKAA2,Tau-protein kinase PRKAA1
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic A Alpha subunit and regulatory B Beta and G Gamma subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from human AMPKA Alpha1/2 around the non-phosphorylation site of Thr183/172.
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Non-human Primate, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:2_polyclonal_antibody-e_ab_30491
