Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Cleaved-CASP3 p17 (D175) Polyclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-30020-20UL
60 ul
£183.00
E-AB-30020-60UL
120 ul
£272.00
E-AB-30020-120UL
200 ul
£420.00
E-AB-30020-200UL
About this Product
SKU:
E-AB-30020
Additional Names:
A830040C14Rik;Apopain;CASP-3;CASP3;CC3;CPP-32;CPP32;CPP32B;Casp3a;Caspase 3;Caspase-3 subunit p12;Cysteine p;apoptosis-related cysteine peptidase;apoptosis-related cysteine protease;apoptosis-related cysteine protease a
Application:
Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Concentration:
1 mg/ml
Extra Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Host:
Rabbit
Immunogen:
Synthesized peptide derived from the Internal region of human Caspase-3 p17
Isotype:
IgG
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Polyclonal Antibody