MMP2 Monoclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-22242-20UL
60 ul
£183.00
E-AB-22242-60UL
120 ul
£272.00
E-AB-22242-120UL
200 ul
£420.00
E-AB-22242-200UL
About this Product
- SKU:
- E-AB-22242
- Additional Names:
- 72 kDa gelatinase,72kD type IV collagenase,CLG 4,CLG 4A,CLG4,CLG4A,Collagenase Type 4 alpha,Collagenase type IV A,Gelatinase A,Gelatinase alpha,Gelatinase neutrophil,Matrix ,Matrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenase
- Application:
- IHC-Paraffin, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- translate.label.attr.clone:
- 1H1
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.
- Host:
- Mouse
- Immunogen:
- Synthetic Peptide of MMP2
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-mmp2_monoclonal_antibody-e_ab_22242
