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Antibodies

BAX Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22212-20UL
60 ul
£183.00
E-AB-22212-60UL
120 ul
£272.00
E-AB-22212-120UL
200 ul
£420.00
E-AB-22212-200UL
About this Product
SKU:
E-AB-22212
Additional Names:
Apoptosis regulator BAX,BAX,BAXA,BCL2 associated X protein,BCL2 associated X protein omega,BCL2 associated X protein transcript variant delta2,BCL2L4,Bax-protein,Baxdelta2G9,Baxdelta2G9omega,Baxdelta2omega,Bcl-2-like protein 4,Bcl2-L-4,membrane isofor
Application:
IHC-Paraffin, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
1C1
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Host:
Mouse
Immunogen:
Synthetic Peptide of Bax
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody