SGK1 Monoclonal Antibody
Product Sizes
20 ul
£118.00
E-AB-22207-20UL
60 ul
£183.00
E-AB-22207-60UL
120 ul
£272.00
E-AB-22207-120UL
200 ul
£420.00
E-AB-22207-200UL
About this Product
- SKU:
- E-AB-22207
- Additional Names:
- OTTHUMP00000017247,Serine/threonine protein kinase SGK,Serine/threonine protein kinase Sgk1,Serine/threonine-protein kinase Sgk1,Serum and glucocorticoid regulated kinase,Serum/,Serum/glucocorticoid regulated kinase,Serum/glucocorticoid regulated kinase 1
- Application:
- IHC-Paraffin, Immunohistochemistry
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- translate.label.attr.clone:
- 4D12
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, KCNA3/Kv1.3 or EAAT1. Isoform 2 exhibited a greater effect on cell plasma membrane expression of ENaC and Na(+) transport than isoform 1.
- Host:
- Mouse
- Immunogen:
- Synthetic Peptide of SGK1
- Isotype:
- IgG
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:p-sgk1_monoclonal_antibody-e_ab_22207
