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Antibodies

Crystallin-alpha C Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22177-20UL
60 ul
£183.00
E-AB-22177-60UL
120 ul
£272.00
E-AB-22177-120UL
200 ul
£420.00
E-AB-22177-200UL
About this Product
SKU:
E-AB-22177
Additional Names:
Alpha crystallin C chain;Alpha-crystallin C chain;CMT2L;CRYAC;Charcot Marie Tooth disease axonal type 2L;Charcot Marie Tooth disease spinal;DHMN 2;DHMN2;E2 induced gene 1 protein;E2-induced gene 1 protein;E2IG1;H11;Heat shock 22kDa protein 8;Heat shock 27
Application:
Western Blot
Buffer:
PBS
translate.label.attr.clone:
2C3
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Host:
Mouse
Immunogen:
Recombinant Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody