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Antibodies

NFKBIB Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22175-20UL
60 ul
£183.00
E-AB-22175-60UL
120 ul
£272.00
E-AB-22175-120UL
200 ul
£420.00
E-AB-22175-200UL
About this Product
SKU:
E-AB-22175
Additional Names:
I kappa B beta,I-kappa-B-beta,IKB beta,IKBB,IkB-B,IkB-beta,IkBbeta,IkappaBbeta,NF kappa BIB,NF-kappa-B inhibitor beta,NF-kappa-BIB,Nfkbib,TR interacting protein 9,TR-intera,Thyroid receptor interacting protein 9,Thyroid receptor-interacting protein 9
Application:
IHC-Paraffin, Immunohistochemistry
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
translate.label.attr.clone:
3E4
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Host:
Mouse
Immunogen:
Recombinant Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody