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Antibodies

c-Fos Monoclonal Antibody

Product Sizes
20 ul
£118.00
E-AB-22158-20UL
60 ul
£183.00
E-AB-22158-60UL
120 ul
£272.00
E-AB-22158-120UL
200 ul
£420.00
E-AB-22158-200UL
About this Product
SKU:
E-AB-22158
Additional Names:
AP 1;Activator protein 1;C FOS;Cellular oncogene c fos;Cellular oncogene fos;FBJ Oste;FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS);FBJ murine osteosarcoma viral oncogene homolog;FBJ murine osteosarcoma viral v fos oncogene homolog
Application:
IHC-Paraffin, Immunohistochemistry, Western Blot
Buffer:
PBS
translate.label.attr.clone:
6A3
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.
Host:
Mouse
Immunogen:
Recombinant Protein
Isotype:
IgG
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Type:
Antibody: Monoclonal Antibody